ISRCTN12845429.

Trial name or title	A placebo‐controlled double‐blind randomised feasibility trial of desmopressin (DDAVP) in critical illness prior to procedures
Methods	Placebo‐controlled double‐blind randomised study
Participants	Inclusion criteria Adult patients (age ≥ 18 years) Platelet count ≤ 100 × 10⁹/L Inpatient on a critical care ward Due to undergo an interventional procedure Exclusion criteria Active bleeding History of ischaemic heart disease (myocardial infarction or angina), stroke, or transient ischaemic attack (TIA) Admission to ICU with traumatic brain injury or seizures Congenital bleeding disorder Pregnant or breastfeeding History of anaphylaxis to desmopressin
Interventions	Intervention: desmopressin Control: ‐
Outcomes	Primary outcome Proportion of eligible patients randomised into study and receiving OCTIM Injection Secondary outcome ‐
Starting date	November 2016
Contact information	‐
Notes	clinicaltrialsregister.eu/ctr‐search/search?query=EUCTR2016‐001126‐33‐GB