NCT00590928.

Trial name or title	Gastric pH in critically ill patients
Methods	Double‐blind parallel‐group randomised controlled study
Participants	Inclusion criteria Critically ill patients Indication for stress ulcer prophylaxis Gastric pH < 4 Exclusion criteria GI bleeding Gastric pH > 4
Interventions	Intervention: esomeprazole 40 mg once daily Control: ranitidine 50 mg every hour
Outcomes	Primary outcome Percentage of time with gastric pH > 4 Secondary outcomes Median gastric pH Incidence of gastrointestinal bleeding Incidence of ventilator‐associated pneumonia Percentage of time with gastric pH > 5
Starting date	July 2004
Contact information	Christian Madl, MD, Medical University of Vienna
Notes	clinicaltrials.gov/ct2/show/record/NCT00590928