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. 2018 Jun 4;2018(6):CD008687. doi: 10.1002/14651858.CD008687.pub2

NCT00702871.

Trial name or title A clinico‐bacteriological study and effect of stress ulcer prophylaxis on occurrence of ventilator associated pneumonia
Methods Parallel‐group open‐label randomised controlled study
Participants Inclusion criteria
  • Age > 12 years

  • Those on mechanical ventilation longer than 48 hours


Exclusion criteria
  • Pre‐existing pneumonia at beginning of ventilation

  • Developing pneumonia within 48 hours of ventilation

  • Patients taking oral antibiotics

Interventions Intervention: ranitidine 50 mg IV 8‐hourly for entire duration of ICU stay
Control: sucralfate 1 g via NG tube 6‐hourly for entire duration of ICU stay
Outcomes Primary outcome
  • Occurrence of ventilator‐associated pneumonia


Secondary outcome
Starting date March 2005
Contact information Rajiv Singla, MD, Maulana Azad Medical College and Lok Nayak Hospital, Delhi, India
Notes clinicaltrials.gov/ct2/show/record/NCT00702871