Comparison 1. All antimicrobial (antibiotic plus non‐antibiotic plus the combination) solutions versus control.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Catheter‐related infection (per 1000 catheter‐days)	27		Rate Ratio (Fixed, 95% CI)	0.45 [0.38, 0.54]
2 Catheter‐related infection (per 1000 dialysis sessions)	2		Rate Ratio (Fixed, 95% CI)	0.49 [0.21, 1.12]
3 Thrombosis (per 1000 catheter‐days)	14		Rate Ratio (Random, 95% CI)	0.79 [0.52, 1.22]
4 Colonisation	2		Rate Ratio (Random, 95% CI)	0.37 [0.04, 3.36]
5 Subgroup analysis: catheter‐related infection (per 1000 catheter‐days) in tunnelled catheters	21		Rate Ratio (Random, 95% CI)	0.40 [0.30, 0.53]
6 Subgroup analysis: catheter‐related infection (per 1000 catheter‐days) in non‐tunnelled catheters	8		Rate Ratio (Random, 95% CI)	0.37 [0.16, 0.86]
7 Subgroup analysis: thrombosis (per 1000 catheter‐days) in tunnelled catheters	10		Rate Ratio (Random, 95% CI)	0.83 [0.50, 1.37]
8 Subgroup analysis: thrombosis (per 1000 catheter‐days) in non‐tunnelled catheters	4		Rate Ratio (Random, 95% CI)	0.66 [0.25, 1.72]