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. 2018 Apr 3;2018(4):CD010597. doi: 10.1002/14651858.CD010597.pub2

Comparison 5. Non‐antibiotic antimicrobial lock solutions versus control.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Catheter‐related infection (per 1000 catheter‐days) 11   Rate Ratio (Random, 95% CI) 0.65 [0.41, 1.05]
2 Catheter‐related infection (per 1000 dialysis sessions) 1   Rate Ratio (Random, 95% CI) Totals not selected
3 Thrombosis (per 1000 catheter‐days) 8   Rate Ratio (Random, 95% CI) 0.85 [0.44, 1.66]
4 Thrombosis (per 1000 dialysis sessions) 1   Rate Ratio (Random, 95% CI) Totals not selected
5 Colonisation 1   Rate Ratio (Random, 95% CI) 0.99 [0.27, 3.68]
6 Subgroup analysis: catheter‐related infection (per 1000 catheter‐days) in tunnelled catheters 9   Rate Ratio (Random, 95% CI) 0.60 [0.40, 0.91]
7 Subgroup analysis: catheter‐related infection (per 1000 catheter‐days) in non‐tunnelled catheters 4   Rate Ratio (Random, 95% CI) 0.93 [0.48, 1.81]
8 Subgroup analysis: thrombosis (per 1000 catheter‐days) in tunnelled catheters 5   Rate Ratio (Random, 95% CI) 1.17 [0.57, 2.41]
9 Subgroup analysis: thrombosis (per 1000 catheter‐days) in non‐tunnelled catheters 4   Rate Ratio (Random, 95% CI) 0.66 [0.25, 1.72]