Al‐Hwiesh 2007.

Methods	Study design: parallel RCT Study duration: February 2005 to July 2006 Duration of follow‐up: 12 months
Participants	Setting: single centre Country: Saudi Arabia Patients on HD who had HD catheter Number (patients/catheters): treatment group (36/39); control group (33/47) Mean age ± SD (years): treatment group (47.4 ± 11.5); control group (45.5 ± 7.4) Sex (M/F): treatment group (22/14); control group (21/12) Exclusion criteria: not reported
Interventions	Treatment group Vancomycin hydrochloride: 25 mg/mL Gentamycin sulphate: 40 mg/mL Heparin: 5000 U/mL Control group Heparin: 5000 U/mL
Outcomes	Bacteraemia Clinical sepsis
Notes	Funding source: not reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Insufficient information to permit judgement
Allocation concealment (selection bias)	Unclear risk	Insufficient information to permit judgement
Blinding of participants and personnel (performance bias) All outcomes	High risk	Open‐label study
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Insufficient information to permit judgement
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Insufficient information to permit judgement
Selective reporting (reporting bias)	Low risk	Study protocol not available but published results include all expected outcomes
Other bias	Low risk	Study appears free of other biases