Dogra 2002.

Methods	Study design: parallel RCT Study duration: May 1999 to June 2001 Duration of follow‐up: 270 days
Participants	Setting: multicentre (2) Country: Australia Participants required insertion of a tunnelled catheter for the maintenance or commencement of HD Number (participants/catheters): treatment group (44/55); control group (39/57) Mean age ± SD (years): treatment group (55.7 ± 2.5); control group (59.3 ± 2.1) Sex (% M/F): treatment group (45/55); control group (47/53) Exclusion criteria: active sepsis; were on parenteral or prolonged (> 5 d) oral antibiotic therapy; allergy to gentamicin and/or citrate
Interventions	Treatment group Gentamicin: 2 mL of 40 mg/mL Tri‐sodium citrate: 1mL of 3.13% Control group Heparin: 5000 U/mL
Outcomes	CRI Infection‐free catheter survival
Notes	Funding source: not reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	"Block randomization using random number tables was performed by Clinical Trials Pharmacists, thereby ensuring allocation concealment"
Allocation concealment (selection bias)	Unclear risk	Insufficient information to permit judgement
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Blinding of participants and personnel
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Blinding of microbiology staff
Incomplete outcome data (attrition bias) All outcomes	Low risk	Missing outcome data balanced in numbers across intervention groups, with similar reasons for missing data across groups;
Selective reporting (reporting bias)	Low risk	Describes the outcome according to objective
Other bias	Unclear risk	Funding source not reported