Plamandon 2005a.

Methods	Study design: crossover RCT Study duration: 4 weeks Duration of follow‐up: not reported
Participants	Setting: not reported Country: Canada Participants with prevalent cuffed double lumen catheters Number: 44 Mean age: 72.9 years Sex (males): 57% Exclusion criteria: not reported
Interventions	Treatment group sodium citrate: 4% Control group Heparin: 5000 U/mL
Outcomes	Thrombosis Catheter dysfunction
Notes	Abstract‐only publication Funding source: not reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Insufficient information to permit judgement
Allocation concealment (selection bias)	Unclear risk	Insufficient information to permit judgement
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Insufficient information to permit judgement
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Insufficient information to permit judgement
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Insufficient information to permit judgement
Selective reporting (reporting bias)	Unclear risk	Insufficient information to permit judgement
Other bias	Unclear risk	Insufficient information to permit judgement