Power 2009.

Methods	Study design: quasi‐RCT Study duration: not reported Duration of follow‐up: not reported
Participants	Setting: multicentre (4) Country: UK Participants who had been on dialysis therapy for longer than 90 days Number (participants/catheters): treatment group (132/132); control group (100/100) Mean age ± SD (years): treatment group I (63 ± 14); control group (62 ± 13) Sex (M/F): treatment group (73/59); control group (59/41) Exclusion criteria: bleeding diathesis; an intervention, or pathological state within 3 months of entry that would heighten the risk of bleeding; hypocalcaemia
Interventions	Treatment group Sodium citrate: 46.7% Control group Heparin: 5000 U/mL
Outcomes	CRI Catheter dysfunction
Notes	Funding source: None
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	High risk	Single random‐ numbers method of odd and even numbers
Allocation concealment (selection bias)	Unclear risk	Insufficient information to permit judgement
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Insufficient information to permit judgement
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Insufficient information to permit judgement
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	All patient data reported
Selective reporting (reporting bias)	High risk	Outcomes of interest reported incompletely
Other bias	Unclear risk	Insufficient information to permit judgement