Bohmer 1988.

Methods	Study design: double‐blinded, randomised Country: Germany Setting: single centre Intention‐to‐treat: not mentioned
Participants	Number of participants randomly assigned: 27 (14 Ginkgo biloba extract, 13 pentoxifylline) Number of participants analysed: 26 Exclusions post randomisation: none Losses to follow‐up: 1 Age: 60.3 ± 7.3 years (range 44 to 72 years) Sex: 24 males, 3 females Inclusion criteria: outpatient; high‐grade stenosis for SFA; 1‐side claudication; PFWD 50 to 200 m; < 30% variance in WD during 3‐week placebo induction phase Exclusion criteria: not mentioned
Interventions	Treatment: pentoxifylline, 1200 mg/d Control: Ginkgo biloba extract, 160 mg/d Duration: 24 weeks
Outcomes	Primary: mean PFWD, TWD Secondary: ABI
Notes	Treadmill protocol: 3 km/h at 5% inclination Mean PFWD and TWD expressed in metres only
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	States 'randomised'; no other information provided
Allocation concealment (selection bias)	Unclear risk	Not mentioned
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Reports 'double blind'; no other information available
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not mentioned
Incomplete outcome data (attrition bias) All outcomes	Low risk	No incomplete outcome data
Selective reporting (reporting bias)	Unclear risk	Protocol not available; insufficient information available to permit judgement
Other bias	Low risk	Study appears free of other bias