Comparison 3. Long‐acting muscarinic antagonists (LAMA) dose head‐to‐head.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Exacerbations (oral corticosteroid)	1	1036	Odds Ratio (M‐H, Fixed, 95% CI)	0.69 [0.40, 1.22]
2 Asthma Quality of Life Questionnaire (AQLQ) total	2	973	Mean Difference (IV, Random, 95% CI)	0.01 [‐0.09, 0.10]
3 Serious adverse events (SAEs) (all)	2	1036	Odds Ratio (M‐H, Random, 95% CI)	1.09 [0.47, 2.49]