Comparison 24. Oral versus vaginal misoprostol (6): all primiparae.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Vaginal delivery not achieved within 24 hours	1	106	Risk Ratio (M‐H, Fixed, 95% CI)	1.25 [1.01, 1.55]
2 Uterine hyperstimulation with FHR changes	1	200	Risk Ratio (M‐H, Fixed, 95% CI)	0.5 [0.05, 5.43]
3 Caesarean section	3	285	Risk Ratio (M‐H, Fixed, 95% CI)	1.62 [1.01, 2.58]
4 Serious neonatal morbidity or perinatal death	3	322	Risk Ratio (M‐H, Fixed, 95% CI)	1.03 [0.67, 1.59]
5 Serious maternal morbidity or death	2	122	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
6 Oxytocin augmentation	1	200	Risk Ratio (M‐H, Fixed, 95% CI)	1.73 [0.87, 3.44]
7 Uterine hyperstimulation without FHR changes	1	200	Risk Ratio (M‐H, Fixed, 95% CI)	2.67 [0.73, 9.76]
8 Instrumental vaginal delivery	1	200	Risk Ratio (M‐H, Fixed, 95% CI)	0.6 [0.23, 1.59]
9 Apgar score < 7 at 5 minutes	1	200	Risk Ratio (M‐H, Fixed, 95% CI)	0.47 [0.23, 1.00]
10 Nausea	1	200	Risk Ratio (M‐H, Fixed, 95% CI)	1.0 [0.14, 6.96]
11 Vomiting	1	200	Risk Ratio (M‐H, Fixed, 95% CI)	1.5 [0.26, 8.79]