Comparison 30. Hourly 20mcg titrated oral misoprostol versus 4‐hrly oral misoprostol 50mcg (7): all women.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Vaginal delivery not achieved within 24 hours	1	64	Risk Ratio (M‐H, Fixed, 95% CI)	1.35 [0.92, 2.00]
2 Caesarean section	1	64	Risk Ratio (M‐H, Fixed, 95% CI)	1.31 [0.77, 2.22]
3 Serious neonatal morbidity or perinatal death	1	64	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
4 Oxytocin augmentation	1	64	Risk Ratio (M‐H, Fixed, 95% CI)	1.0 [0.59, 1.68]
5 Uterine hyperstimulation without FHR changes	1	64	Risk Ratio (M‐H, Fixed, 95% CI)	4.0 [0.92, 17.40]
6 Uterine rupture	1	64	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
7 Apgar score < 7 at 5 minutes	1	64	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
8 Neonatal intensive care unit admission	1	64	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
9 Nausea	1	64	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
10 Vomiting	1	64	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
11 Diarrhoea	1	64	Risk Ratio (M‐H, Fixed, 95% CI)	3.0 [0.13, 71.00]
12 Postpartum haemorrhage	1	64	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]