| Methods |
"Pharmacy prepared and distributed the medication according to the schedule"; study described as double‐blind. |
| Participants |
160 women requiring induction at term; 50 had ruptured membranes and 79 were nulliparous. |
| Interventions |
Oral misoprostol 200 mcg or placebo as a single dose followed 12 hours later by iv oxytocin if not in labour. |
| Outcomes |
Labour and birth outcomes.
Neonatal outcomes. |
| Notes |
4 women were excluded after randomisation. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Low risk |
The randomisation was performed using a computer‐generated random number table. |
| Allocation concealment (selection bias) |
Unclear risk |
Method of allocation concealment was not described. |
| Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
Insufficient information to permit judgement of ‘Low risk’ or ‘High risk’. |
| Selective reporting (reporting bias) |
Unclear risk |
Insufficient information to permit judgement of ‘Low risk’ or ‘High risk’. |
| Other bias |
Unclear risk |
Insufficient information to permit judgement of ‘Low risk’ or ‘High risk’. |
| Blinding of participants and personnel (performance bias)
All outcomes |
Low risk |
The study described as double‐blinded. |
| Blinding of outcome assessment (detection bias)
All outcomes |
Low risk |
The study described as double‐blinded. |
