Wing 2004.

Methods	Sequentially‐numbered, sealed envelopes.
Participants	200 women at any gestation with favourable cervices (BS > 6) and intact or recently ruptured membranes (less than 24 hours).
Interventions	Oral misoprostol 100 mcg 4‐hourly (max x 6) or iv oxytocin infusion ("standard regimen").
Outcomes	Labour and delivery outcomes. Neonatal outcomes.
Notes	2 women in misoprostol group accidentally received extra‐amniotic saline.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Treatment allocation was determined with the use of a computer generated random number table.
Allocation concealment (selection bias)	Low risk	Sequentially‐numbered, sealed envelopes.
Incomplete outcome data (attrition bias) All outcomes	Low risk	Only two women were excluded from analysis because of deviation from study protocol.
Selective reporting (reporting bias)	Unclear risk	Insufficient information about the sequence generation process to permit judgement of ‘Low risk’ or ‘High risk’
Other bias	Unclear risk	Insufficient information about the sequence generation process to permit judgement of ‘Low risk’ or ‘High risk’
Blinding of participants and personnel (performance bias) All outcomes	High risk	The study was not blinded.
Blinding of outcome assessment (detection bias) All outcomes	High risk	The study was not blinded.

ARM: artificial rupture of membranes
 BS: Bishop score
 CS: caesarean section
 CTG: cardiotocography
 FHR: fetal heart rate
 hr(s): hour(s)
 IUGR: intrauterine growth restriction
 iv: intravenous
 max: maximum
 mcg: micrograms
 mU/min: milliunits per minute
 mU/mL: milliunits per millilitre
 mec: meconium
 mg: milligram
 NICU: Neonatal intensive care unit
 PGE2: prostaglandin cream
 po: oral administration ('per oram')
 PROM: premature rupture of membranes
 pv: vaginal administration ('per vaginum')
 SD: standard deviation
 SROM: spontaneous rupture of membranes
 vs: versus