CENTRAL (CRS Web)	Cochrane ENT Register (CRS Web)	MEDLINE (Ovid)
1 MESH DESCRIPTOR Ear EXPLODE ALL AND CENTRAL:TARGET 2 MESH DESCRIPTOR Ear Diseases EXPLODE ALL AND CENTRAL:TARGET 3 (("otitis media" or OME)):AB,EH,KW,KY,MC,MH,TI,TO AND CENTRAL:TARGET 4 MESH DESCRIPTOR Tympanic Membrane Perforation EXPLODE ALL AND CENTRAL:TARGET 5 MESH DESCRIPTOR Tympanic Membrane EXPLODE ALL AND CENTRAL:TARGET 6 ("ear drum*" or eardrum* or tympanic):AB,EH,KW,KY,MC,MH,TI,TO AND CENTRAL:TARGET 7 #5 OR #6 8 ((perforat* or hole or ruptur*).):AB,EH,KW,KY,MC,MH,TI,TO AND CENTRAL:TARGET 9 #7 AND #8 10 #2 OR #1 OR #3 OR #4 OR #9 11 MESH DESCRIPTOR Suppuration EXPLODE ALL AND CENTRAL:TARGET 12 (suppurat* or pus or purulen* or discharg* or mucosal or otorrh* or otorh* or otoliquor* or active or weep* or wet or moist or discomfort or earach* or mucopurulen*):AB,EH,KW,KY,MC,MH,TI,TO AND CENTRAL:TARGET 13 (pain*):AB,TI AND CENTRAL:TARGET 14 #12 OR #11 OR #13 15 #14 AND #10 16 MESH DESCRIPTOR Otitis Media, Suppurative EXPLODE ALL AND CENTRAL:TARGET 17 (CSOM or earach*):AB,EH,KW,KY,MC,MH,TI,TO AND CENTRAL:TARGET 18 (((ear or ears or aural) near (suppurat* or pus or purulen* or discharg* or mucosal or otorrh* or otorh* or otoliquor* or active or weep* or wet or moist or mucopurulen* or pain* or discomfort))):AB,EH,KW,KY,MC,MH,TI,TO AND CENTRAL:TARGET 19 #16 OR #15 OR #17 OR #18 20 (((ear or ears or aural) near (toilet* or care or hygiene or syring* or irrigat* or probe or swab* or wash* or clean* or clear* or suck or suction))):AB,EH,KW,KY,MC,MH,TI,TO AND CENTRAL:TARGET 21 ((microsuction* or propulse or "pro pulse")):AB,EH,KW,KY,MC,MH,TI,TO AND CENTRAL:TARGET 22 ((dry near mop*)):AB,EH,KW,KY,MC,MH,TI,TO AND CENTRAL:TARGET 23 (((cotton or tissue) near (wool or bud or spear*))):AB,EH,KW,KY,MC,MH,TI,TO AND CENTRAL:TARGET 24 ((chrome near syring*)):AB,EH,KW,KY,MC,MH,TI,TO AND CENTRAL:TARGET 25 ((jobson near horn)):AB,EH,KW,KY,MC,MH,TI,TO AND CENTRAL:TARGET 26 #20 OR #21 OR #22 OR #23 OR #24 OR #25 27 #26 AND #19	1 ("otitis media" or OME):AB,EH,KW,KY,MC,MH,TI,TO AND INREGISTER 2 (("ear drum*" or eardrum* or tympanic)):AB,EH,KW,KY,MC,MH,TI,TO AND INREGISTER 3 (perforat* or hole or ruptur*):AB,EH,KW,KY,MC,MH,TI,TO AND INREGISTER 4 #2 AND #3 AND INREGISTER 5 #4 OR #1 AND INREGISTER 6 (suppurat* or pus or purulen* or discharg* or mucosal or otorrh* or otorh* or otoliquor* or active or weep* or wet or moist or discomfort or earach* or mucopurulen*):AB,EH,KW,KY,MC,MH,TI,TO AND INREGISTER 7 (pain):AB,TI,TO AND INREGISTER 8 #6 OR #7 AND INREGISTER 9 (chronic* or persist* or recurr* or repeat*):AB,EH,KW,KY,MC,MH,TI,TO AND INREGISTER 10 #5 AND #8 AND #9 AND INREGISTER 11 (csom or earach*):AB,EH,KW,KY,MC,MH,TI,TO AND INREGISTER 12 (((ear or ears or aural) NEAR (suppurat* or pus or purulen* or discharg* or mucosal or otorrh* or otorh* or otoliquor* or active or weep* or wet or moist or mucopurulen* or pain* or discomfort))):AB,EH,KW,KY,MC,MH,TI,TO AND INREGISTER 13 #10 OR #11 OR #12 AND INREGISTER 14 (((ear or ears or aural) near (toilet* or care or hygiene or syring* or irrigat* or probe or swab* or wash* or clean* or clear* or suck or suction))):AB,EH,KW,KY,MC,MH,TI,TO AND INREGISTER 15 ((microsuction* or propulse or "pro pulse")):AB,EH,KW,KY,MC,MH,TI,TO AND INREGISTER 16 ((dry near mop*)):AB,EH,KW,KY,MC,MH,TI,TO AND INREGISTER 17 (((cotton or tissue) near (wool or bud or spear*))):AB,EH,KW,KY,MC,MH,TI,TO AND INREGISTER 18 ((jobson near horn)):AB,EH,KW,KY,MC,MH,TI,TO AND INREGISTER 19 ((chrome near syring*)):AB,EH,KW,KY,MC,MH,TI,TO AND INREGISTER 20 #15 OR #14 OR #16 OR #17 OR #19 OR #18 AND INREGISTER 21 #13 AND #20 AND INREGISTER	1 exp Ear Diseases/ 2 exp Ear/ 3 ("otitis media" or OME).ab,ti. 4 exp Tympanic Membrane Perforation/ 5 exp Tympanic Membrane/ 6 ("ear drum*" or eardrum* or tympanic).ab,ti. 7 5 or 6 8 (perforat* or hole or ruptur*).ab,ti. 9 7 and 8 10 1 or 2 or 3 or 4 or 9 11 exp Suppuration/ 12 (suppurat* or pus or purulen* or discharg* or mucosal or otorrh* or otorh* or otoliquor* or active or weep* or moist or wet or mucopurulen* or discomfort or pain* or earach*).ab,ti. 13 11 or 12 14 10 and 13 15 exp Otitis Media, Suppurative/ 16 (CSOM or earach*).ab,ti. 17 ((ear or ears or aural) adj3 (suppurat* or pus or purulen* or discharg* or mucosal or otorrh* or otorh* or otoliquor* or active or weep* or wet or moist or mucopurulen* or pain* or discomfort)).ab,ti. 18 14 or 15 or 16 or 17 19 ((ear or ears or aural) adj3 (toilet* or care or hygiene or syring* or irrigat* or probe or swab* or wash* or clean* or clear* or suck or suction)).ab,ti. 20 (microsuction* or propulse or "pro pulse").ab,ti. 21 (dry adj3 mop*).ab,ti. 22 ((cotton or tissue) adj3 (wool or bud or spear*)).ab,ti. 23 (jobson adj3 horn).ab,ti. 24 (chrome adj3 syring*).ab,ti. 25 19 or 20 or 21 or 22 or 23 or 24 26 18 and 25
Embase (Ovid)	CINAHL (EBSCO)
1 exp ear disease/ 2 exp ear/ 3 ("otitis media" or OME).ab,ti. 4 exp eardrum perforation/ 5 exp eardrum/ 6 ("ear drum*" or eardrum* or tympanic).ab,ti. 7 5 or 6 8 (perforat* or hole or ruptur*).ab,ti. 9 7 and 8 10 1 or 2 or 3 or 4 or 9 11 exp suppuration/ 12 (suppurat* or pus or purulen* or discharg* or mucosal or otorrh* or otorh* or otoliquor* or active or weep* or moist or wet or mucopurulen* or discomfort or pain* or earach*).ab,ti. 13 11 or 12 14 10 and 13 15 exp suppurative otitis media/ 16 (CSOM or earach*).ab,ti. 17 ((ear or ears or aural) adj3 (suppurat* or pus or purulen* or discharg* or mucosal or otorrh* or otorh* or otoliquor* or active or weep* or wet or moist or mucopurulen* or pain* or discomfort)).ab,ti. 18 14 or 15 or 16 or 17 19 ((ear or ears or aural) adj3 (toilet* or care or hygiene or syring* or irrigat* or probe or swab* or wash* or clean* or clear* or suck or suction)).ab,ti. 20 (microsuction* or propulse or "pro pulse").ab,ti. 21 (dry adj3 mop*).ab,ti. 22 ((cotton or tissue) adj3 (wool or bud or spear*)).ab,ti. 23 (jobson adj3 horn).ab,ti. 24 (chrome adj3 syring*).ab,ti. 25 19 or 20 or 21 or 22 or 23 or 24 26 18 and 25	S25 S17 AND S24 S24 S18 OR S19 OR S20 OR S21 OR S22 OR S23 S23 TX (chrome N3 syring*) S22 TX (chrome N3 syring*) S21 TX ((cotton or tissue) N3 (wool or bud or spear*)) S20 TX dry N3 mop*) S19 TX (microsuction* or propulse or "pro pulse") S18 TX ((ear or ears or aural) N3 (toilet* or care or hygiene or syring* or irrigat* or probe or swab* or wash* or clean* or clear* or suck or suction)) S17 S14 OR S15 OR S16 S16 TX ((ear or ears or aural) N3 (suppurat* or pus or purulen* or discharg* or mucosal or otorrh* or otorh* or otoliquor* or active or weep* or wet or moist or mucopurulen* or pain* or discomfort)) S15 TX CSOM or earach* S14 S10 AND S13 S13 S11 OR S12 S12 TX suppurat* or pus or purulen* or discharg* or mucosal or otorrh* or otorh* or otoliquor* or active or weep* or moist or wet or mucopurulen* or discomfort or pain* or earach*) S11 (MH "Suppuration+") S10 S1 OR S2 OR S3 OR S4 OR S9 S9 S7 AND S8 S8 TX perforat* or hole or ruptur* S7 S5 OR S6 S6 TX "ear drum*" or eardrum* or tympanic S5 (MH "Tympanic Membrane") S4 (MH "Tympanic Membrane Perforation") S3 TX "otitis media" or OME S2 (MH "Ear+") S1 (MH "Ear Diseases+")