IRCT138904224359N1.
Trial name or title | Effect of Vitamin E and C supplements on improving asthma |
Methods | Randomised controlled trial |
Participants | History of at least 1 year asthma, age 18 to 50 years Exclusion criteria: suffering from diseases other than asthma, smoking, consumption of contraceptive pills |
Interventions | 800 mg of vitamin C daily for 12 weeks versus placebo (study also includes a vitamin E condition and a vitamin E + vitamin C condition) |
Outcomes | Asthma severity and serum levels |
Starting date | November 2010 |
Contact information | Dr Hesamodin Nabavi Zadeh Yasuj University of Medical Sciences |
Notes | Study description stated as: "The purpose of this double blind clinical trial is to determine the effect of vitamin E & C, alone and in combination, on the improvement of asthma. 80 asthmatic patients, referred to Mofateh Special Clinics and Yasuj Imam Sajjad Hospital, will be randomly assigned into one of following groups to receive 400 mg Vitamin E per day, 800 mg vitamin C, 400 mg Vitamin E as well as 800 mg vitamin C, or placebo for 12 weeks. Holms‐Rahe questionnaire was used to investigate daily stress. Dietary intake is measured using 24‐hour dietary recalls questionnaire and respiratory factors are measured by peak flow meter and Spiro meter. Severity of asthma and the serum levels of vitamin C and E are measured before and after the intervention." Study results not posted at time of completion of this review |