10. Dexamethasone 0.30 mg per kg compared to dexamethasone 0.15 mg per kg for croup.

Dexamethasone 0.30 mg per kg compared to dexamethasone 0.15 mg per kg for croup
Patient or population: children with croup Intervention: dexamethasone 0.30 mg per kg Comparison: dexamethasone 0.15 mg per kg
Outcomes	Anticipated absolute effects* (95% CI)		Relative effect (95% CI)	№ of participants (studies)	Certainty of the evidence (GRADE)
	Dexamethasone 0.15 mg per kg	Dexamethasone 0.30 mg per kg
Return visits or (re)admissions or both	Study population		RR 0.94 (0.06 to 14.27)	60 (1 RCT)	⊕⊝⊝⊝ VERY LOWa, b
	34 per 1000	32 per 1000 (2 to 492)
Adverse events	Geelhoed 1995b did not report collecting adverse events data.
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: confidence interval; RCT: randomised controlled trial; RR: risk ratio
GRADE Working Group grades of evidence High certainty: We are very confident that the true effect lies close to that of the estimate of the effect. Moderate certainty: We are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different. Low certainty: Our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect. Very low certainty: We have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect.

^aWe downgraded by one level for inconsistency. As there was only one study in the analysis, there was no evidence of consistency.
 ^bWe downgraded by two levels for imprecision. The sample size was small (did not meet the optimal information size). The effect estimate included significant benefit, the null effect, and potential harm for 0.30 mg/kg compared to 0.15 mg/kg dexamethasone.