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. 2018 Jul 5;2018(7):CD011849. doi: 10.1002/14651858.CD011849.pub2

Comparison 15. Subgroup analysis: type of control ‐ adults.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 PTSD symptoms at endpoint 16 1272 Std. Mean Difference (IV, Random, 95% CI) ‐1.07 [‐1.34, ‐0.79]
1.1 EMDR vs wait list 2 99 Std. Mean Difference (IV, Random, 95% CI) ‐2.01 [‐2.50, ‐1.52]
1.2 IPT vs wait list 1 20 Std. Mean Difference (IV, Random, 95% CI) ‐1.45 [‐2.46, ‐0.43]
1.3 CBT vs wait list 8 696 Std. Mean Difference (IV, Random, 95% CI) ‐1.08 [‐1.47, ‐0.68]
1.4 CBT vs no treatment 2 52 Std. Mean Difference (IV, Random, 95% CI) ‐0.43 [‐0.98, 0.12]
1.5 TFT vs wait list 1 145 Std. Mean Difference (IV, Random, 95% CI) ‐1.27 [‐1.63, ‐0.91]
1.6 CBT vs TAU/enhanced usual care 2 260 Std. Mean Difference (IV, Random, 95% CI) ‐0.56 [‐0.81, ‐0.31]
2 PTSD symptoms at 1 to 4 months 17 1590 Std. Mean Difference (IV, Random, 95% CI) ‐0.49 [‐0.68, ‐0.31]
2.1 EMDR vs wait list 1 64 Std. Mean Difference (IV, Random, 95% CI) ‐1.76 [‐2.34, ‐1.18]
2.2 CBT vs wait list 13 1160 Std. Mean Difference (IV, Random, 95% CI) ‐0.35 [‐0.49, ‐0.21]
2.3 IPT vs TAU 1 38 Std. Mean Difference (IV, Random, 95% CI) ‐0.99 [‐1.67, ‐0.32]
2.4 CBT vs no treatment 1 22 Std. Mean Difference (IV, Random, 95% CI) ‐1.12 [‐2.04, ‐0.21]
2.5 CBT vs TAU/enhanced usual care 1 306 Std. Mean Difference (IV, Random, 95% CI) ‐0.63 [‐0.86, ‐0.40]
3 PTSD symptoms ≥ 6 months 5 400 Std. Mean Difference (IV, Random, 95% CI) ‐0.37 [‐0.61, ‐0.14]
3.1 Trauma/Supportive counselling vs wait list 1 188 Std. Mean Difference (IV, Random, 95% CI) ‐0.22 [‐0.57, 0.12]
3.2 Trauma/Supportive counselling vs no treatment 1 62 Std. Mean Difference (IV, Random, 95% CI) ‐0.74 [‐1.46, ‐0.02]
3.3 CBT vs no treatment 3 150 Std. Mean Difference (IV, Random, 95% CI) ‐0.45 [‐0.82, ‐0.09]
4 Anxiety symptoms at endpoint 4 535 Std. Mean Difference (IV, Random, 95% CI) ‐0.76 [‐1.10, ‐0.42]
4.1 CBT vs wait list 3 326 Std. Mean Difference (IV, Random, 95% CI) ‐0.92 [‐1.61, ‐0.23]
4.2 CBT vs TAU/enhanced usual care 1 209 Std. Mean Difference (IV, Random, 95% CI) ‐0.74 [‐1.02, ‐0.45]
5 Anxiety symptoms at 1 to 4 months 6 969 Std. Mean Difference (IV, Random, 95% CI) ‐0.43 [‐0.71, ‐0.15]
5.1 CBT vs wait list 5 663 Std. Mean Difference (IV, Random, 95% CI) ‐0.35 [‐0.67, ‐0.03]
5.2 CBT vs TAU/enhanced usual care 1 306 Std. Mean Difference (IV, Random, 95% CI) ‐0.74 [‐0.97, ‐0.51]
6 Anxiety symptoms ≥ 6 months 1 188 Std. Mean Difference (IV, Random, 95% CI) ‐0.18 [‐0.52, 0.16]
6.1 Trauma/Supportive counselling vs wait list 1 188 Std. Mean Difference (IV, Random, 95% CI) ‐0.18 [‐0.52, 0.16]
7 Depressive symptoms at endpoint 14 1254 Std. Mean Difference (IV, Random, 95% CI) ‐0.86 [‐1.06, ‐0.67]
7.1 EMDR vs wait list 2 99 Std. Mean Difference (IV, Random, 95% CI) ‐1.43 [‐1.88, ‐0.99]
7.2 CBT vs wait list 8 696 Std. Mean Difference (IV, Random, 95% CI) ‐0.85 [‐1.08, ‐0.61]
7.3 IPT vs wait list 2 229 Std. Mean Difference (IV, Random, 95% CI) ‐0.84 [‐1.60, ‐0.08]
7.4 CBT vs no treatment 1 22 Std. Mean Difference (IV, Random, 95% CI) 0.11 [‐0.73, 0.95]
7.5 CBT vs TAU/enhanced usual care 1 208 Std. Mean Difference (IV, Random, 95% CI) ‐0.89 [‐1.18, ‐0.60]
8 Depressive symptoms at 1 to 4 months 15 1386 Std. Mean Difference (IV, Random, 95% CI) ‐0.42 [‐0.63, ‐0.21]
8.1 EMDR vs wait list 1 64 Std. Mean Difference (IV, Random, 95% CI) ‐1.21 [‐1.74, ‐0.67]
8.2 CBT vs wait list 11 956 Std. Mean Difference (IV, Random, 95% CI) ‐0.27 [‐0.45, ‐0.08]
8.3 IPT vs TAU 1 38 Std. Mean Difference (IV, Random, 95% CI) ‐0.77 [‐1.43, ‐0.11]
8.4 CBT vs no treatment 1 22 Std. Mean Difference (IV, Random, 95% CI) ‐1.07 [‐1.98, ‐0.16]
8.5 CBT vs TAU/enhanced usual care 1 306 Std. Mean Difference (IV, Random, 95% CI) ‐0.85 [‐1.08, ‐0.62]
9 Depressive symptoms ≥ 6 months 2 242 Std. Mean Difference (IV, Random, 95% CI) ‐0.20 [‐0.49, 0.09]
9.1 Trauma/Supportive counselling vs wait list 1 188 Std. Mean Difference (IV, Random, 95% CI) ‐0.26 [‐0.61, 0.08]
9.2 CBT vs no treatment 1 54 Std. Mean Difference (IV, Random, 95% CI) ‐0.04 [‐0.58, 0.49]
10 Dropout 25 2801 Risk Ratio (M‐H, Random, 95% CI) 0.98 [0.81, 1.19]
10.1 EMDR vs wait list 2 127 Risk Ratio (M‐H, Random, 95% CI) 0.75 [0.40, 1.42]
10.2 CBT vs wait list 14 1575 Risk Ratio (M‐H, Random, 95% CI) 1.02 [0.76, 1.38]
10.3 CBT vs TAU/enhanced usual care 2 406 Risk Ratio (M‐H, Random, 95% CI) 1.17 [0.99, 1.39]
10.4 IPT vs wait list 2 231 Risk Ratio (M‐H, Random, 95% CI) 0.61 [0.30, 1.27]
10.5 CBT vs no treatment 2 66 Risk Ratio (M‐H, Random, 95% CI) 9.47 [1.29, 69.52]
10.6 Trauma/Supportive counselling vs no treatment 1 138 Risk Ratio (M‐H, Random, 95% CI) 0.78 [0.57, 1.08]
10.7 IPT vs TAU 1 49 Risk Ratio (M‐H, Random, 95% CI) 2.17 [0.65, 7.23]
10.8 Trauma/Supportive counselling vs wait list 1 209 Risk Ratio (M‐H, Random, 95% CI) 0.67 [0.29, 1.56]
11 Functional impairment at endpoint 5 686 Std. Mean Difference (IV, Random, 95% CI) ‐0.55 [‐0.80, ‐0.30]
11.1 CBT vs wait list 3 425 Std. Mean Difference (IV, Random, 95% CI) ‐0.48 [‐0.91, ‐0.06]
11.2 CBT vs TAU/enhanced usual care 2 261 Std. Mean Difference (IV, Random, 95% CI) ‐0.68 [‐0.93, ‐0.43]
12 Functional impairment at 1 to 4 months 7 1061 Std. Mean Difference (IV, Random, 95% CI) ‐0.36 [‐0.55, ‐0.16]
12.1 CBT vs wait list 6 758 Std. Mean Difference (IV, Random, 95% CI) ‐0.29 [‐0.45, ‐0.12]
12.2 CBT vs TAU/enhanced usual care 1 303 Std. Mean Difference (IV, Random, 95% CI) ‐0.67 [‐0.90, ‐0.44]
13 Functional impairment ≥ 6 months 1 188 Std. Mean Difference (IV, Random, 95% CI) ‐0.25 [‐0.59, 0.09]
13.1 Trauma/Supportive counselling vs wait list 1 188 Std. Mean Difference (IV, Random, 95% CI) ‐0.25 [‐0.59, 0.09]
14 Quality of life at endpoint 4 325 Std. Mean Difference (IV, Random, 95% CI) ‐0.73 [‐1.22, ‐0.25]
14.1 CBT vs wait list ‐ Adults 3 287 Std. Mean Difference (IV, Random, 95% CI) ‐0.71 [‐1.35, ‐0.07]
14.2 IPT vs wait list ‐ Adults 1 38 Std. Mean Difference (IV, Random, 95% CI) ‐0.88 [‐1.55, ‐0.21]
15 Diagnosis of PTSD 4 402 Risk Ratio (M‐H, Random, 95% CI) 1.07 [0.43, 2.68]
15.1 Trauma/Supportive counselling vs wait list 1 139 Risk Ratio (M‐H, Random, 95% CI) 2.27 [0.88, 5.85]
15.2 IPT vs TAU 1 49 Risk Ratio (M‐H, Random, 95% CI) 0.31 [0.09, 1.02]
15.3 CBT vs wait list 2 214 Risk Ratio (M‐H, Random, 95% CI) 1.28 [0.28, 5.77]
16 Diagnosis of depression 1 49 Risk Ratio (M‐H, Random, 95% CI) 0.30 [0.11, 0.80]
16.1 IPT vs wait list 1 49 Risk Ratio (M‐H, Random, 95% CI) 0.30 [0.11, 0.80]
17 Coping at endpoint 2 151 Std. Mean Difference (IV, Random, 95% CI) ‐0.27 [‐0.60, 0.05]
17.1 CBT vs wait list 2 151 Std. Mean Difference (IV, Random, 95% CI) ‐0.27 [‐0.60, 0.05]
18 Coping at 1 to 4 months 2 121 Std. Mean Difference (IV, Random, 95% CI) 0.07 [‐0.49, 0.64]
18.1 CBT vs wait list 2 121 Std. Mean Difference (IV, Random, 95% CI) 0.07 [‐0.49, 0.64]