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Unless otherwise stated, search terms are free text terms. '$': stands for any character; '?': substitutes one or no character; adj: adjacent (i.e. number of words within range of search term); exp: exploded MeSH; MeSH: medical subject heading (MEDLINE medical index term); pt: publication type; sh: MeSH; tw: text word; ot: original title.

The Cochrane Library (CENTRAL)

#1 MeSH descriptor Diabetes mellitus explode all trees #2 diabet* in All Text #3 (#1 or #2) #4 MeSH descriptor peripheral nervous system diseases explode all trees #5 MeSH descriptor Polyneuropathies explode all trees #6 ((peripheral in All Text and (nervous in All Text near/6 diseas* in All Text)) or (peripheral in All Text and (nervous in All Text near/6 disorder* in All Text))) #7 polyneuropath* in All Text #8 (#4 or #5 or #6 or #7) #9 (#3 and #8) #10 MeSH descriptor Diabetic neuropathies explode all trees #11 ((diabet* in All Text near/6 neuropath* in All Text) or (diabet* in All Text near/6 polyneuropath* in All Text)) #12 (#10 or #11) #13 (#9 or #12) #14 (tactile in All Text and circumferential in All Text and discriminator in All Text) #15 (biothesiometer in All Text or neurothesiometer in All Text or maxivibrometer in All Text or vibrameter in All Text or vibratron in All Text or (Case in All Text and IV in All Text and system in All Text)) #16 ((light in All Text and (touch in All Text near/3 perception* in All Text)) or (vibration in All Text near/3 perception* in All Text)) #17 ((nerve in All Text and (conduction in All Text near/3 test* in All Text)) or (nerve in All Text and (conduction in All Text near/3 examination* in All Text)) or (nerve in All Text and (conduction in All Text near/3 stud* in All Text))) #18 (tuning in All Text and fork* in All Text) #19 (quantitative in All Text and (sensory in All Text near/6 test* in All Text)) #20 ((vibration* in All Text near/6 threshold in All Text) or (perception* in All Text near/6 threshold in All Text)) #21 (simple in All Text and test* in All Text) #22 (monofilament* in All Text or (vibration in All Text and perception* in All Text) or (ankle in All Text and reflex* in All Text)) #23 (nerve in All Text and conduction in All Text and velocit* in All Text) #24 (vibration in All Text near/6 test* in All Text) #25 (SWMT in All Text or VPT in All Text or QST in All Text or TCD in All Text) #26 ((latency in All Text near/3 diagnos* in All Text) or (velocity in All Text near/3 diagnos* in All Text) or (amplitude in All Text near/3 diagnos* in All Text)) #27 ((large in All Text and (fiber in All Text near/6 function* in All Text)) or (large in All Text and (fiber in All Text near/6 disfunction* in All Text)) or (large in All Text and (fiber in All Text near/6 dysfunction* in All Text)) or (large in All Text and (fiber in All Text near/6 impairment* in All Text))) #28 ((large in All Text and (fibre in All Text near/6 function* in All Text)) or (large in All Text and (fibre in All Text near/6 disfunction* in All Text)) or (large in All Text and (fibre in All Text near/6 dysfunction* in All Text)) or (large in All Text and (fibre in All Text near/6 impairment in All Text))) #29 ((Semmes‐Weinstein in All Text and (monofilament in All Text near/6 test* in All Text)) or (steel in All Text and (ball‐bearing in All Text near/6 test* in All Text)) or (steel in All Text and ball in All Text and (bearing in All Text near/6 test* in All Text))) #30 ((sensor* in All Text near/6 test* in All Text) or (sensor* in All Text near/6 devic* in All Text)) #31 ((neuro in All Text near/3 test* in All Text) or (neuro* in All Text near/3 devic* in All Text)) #32 (vibration* in All Text near/3 sensation* in All Text) #33 (vibratory in All Text near/3 perception* in All Text) #34 vibratometry in All Text #35 (vibrotactile in All Text near/3 measurement* in All Text) #36 (nylon in All Text near/3 filament* in All Text) #37 (Frey* in All Text or neuropen in All Text or (ipswich in All Text and touch in All Text and test* in All Text) or IpTT in All Text) #38 ((tactile in All Text near/3 perception* in All Text and (threshold in All Text) or (tactile in All Text near/3 sensation* in All Text)) #39 ((pressure in All Text near/3 sensation* in All Text) or (pressure in All Text near/3 perception* in All Text)) #40 (tendon in All Text near/3 reflex* in All Text) #41 ((ankle in All Text and jerk in All Text) or (Achilles in All Text and tendon in All Text and reflex* in All Text)) #42 (#14 or #15 or #16 or #17 or #18 or #19 or #20 or #21 or #22 or #23 or #24 or #25) #43 (#26 or #27 or #28 or #29 or #30 or #31 or #32 or #33 or #34 or #35 or #36 or #37 or #38 or #39 or #40 or #41) #44 (#42 or #43) #45 (#13 and #44)

MEDLINE

1 exp Diabetes Mellitus/ 2 diabet*.tw,ot. 3 1 or 2 4 exp Peripheral Nervous System Diseases/ 5 (peripheral nervous adj6 (diseas* or disorder*)).tw,ot. 6 exp Polyneuropathies/ 7 polyneuropath*.tw,ot. 8 or/4‐7 9 3 and 8 10 exp Diabetic Neuropathies/ 11 (diabet* adj6 (neuropath* or polyneuropath*)).tw,ot. 12 10 or 11 13 9 or 12 14 (quantitative sensory test* or tactile circumferential discriminator).tw,ot. 15 (biothesiometer or neurothesiometer or maxivibrometer or vibrameter or vibratron or Case IV system).tw,ot. 16 ((light touch or vibration) adj3 perception*).tw,ot. 17 (nerve conduction adj3 (test* or examination* or stud*)).tw,ot. 18 tuning fork*.tw,ot. 19 (quantitative sensory adj6 test*).tw,ot. 20 ((vibration* or perception*) adj6 threshold*).tw,ot. 21 simple test*.tw,ot. 22 (monofilament* or vibration perception* or ankle reflex*).tw,ot. 23 nerve conduction velocit*.tw,ot. 24 (vibration adj6 test*).tw,ot. 25 (SWMT or VPT or QST or TCD).tw,ot. 26 ((latency or velocity or amplitude) adj3 diagnos*).tw,ot. 27 ((large fiber or large fibre) adj6 (function* or disfunction* or dysfunction* or impairment*)).tw,ot. 28 ((Semmes‐Weinstein monofilament or steel ball‐bearing or two‐point discriminator) adj6 test*).tw,ot. 29 (steel adj6 (ball‐bearing or ball bearing)).tw,ot. 30 ((sensor* or neuro*) adj3 (test* or devic*)).tw,ot. 31 (vibration* adj3 sensation*).tw,ot. 32 (vibratory adj3 perception*).tw,ot. 33 vibratometry.tw,ot. 34 (vibrotactile adj3 measurement*).tw,ot. 35 (nylon adj3 filament*).tw,ot. 36 (Frey* or neuropen or ipswich touch test* or IpTT).tw,ot. 37 (tactile adj3 (perception threshold* or sensation*)).tw,ot. 38 (pressure adj3 (sensation* or perception*)).tw,ot. 39 (tendon adj3 reflex*).tw,ot. 40 (ankle jerk or Achilles tendon reflex*).tw,ot. 41 or/14‐40 42 exp ankle/ or exp achilles tendon/ 43 exp reflex/ 44 42 and 43 45 41 or 44 46 13 and 45 47 limit 46 to humans

EMBASE

1 exp Diabetes Mellitus/ 2 diabet*.tw,ot. 3 1 or 2 4 exp Peripheral Nervous System Diseases/ 5 (peripheral nervous adj6 (diseas* or disorder*)).tw,ot. 6 exp Polyneuropathies/ 7 polyneuropath*.tw,ot. 8 or/4‐7 9 3 and 8 10 exp Diabetic Neuropathies/ 11 (diabet* adj6 (neuropath* or polyneuropath*)).tw,ot. 12 10 or 11 13 9 or 12 14 (quantitative sensory test* or tactile circumferential discriminator).tw,ot. 15 (biothesiometer or neurothesiometer or maxivibrometer or vibrameter or vibratron or Case IV system).tw,ot. 16 ((light touch or vibration) adj3 perception*).tw,ot. 17 (nerve conduction adj3 (test* or examination* or stud*)).tw,ot. 18 tuning fork*.tw,ot. 19 (quantitative sensory adj6 test*).tw,ot. 20 ((vibration* or perception*) adj6 threshold*).tw,ot. 21 simple test*.tw,ot. 22 (monofilament* or vibration perception* or ankle reflex*).tw,ot. 23 nerve conduction velocit*.tw,ot. 24 (vibration adj6 test*).tw,ot. 25 (SWMT or VPT or QST or TCD).tw,ot. 26 ((latency or velocity or amplitude) adj3 diagnos*).tw,ot. 27 ((large fiber or large fibre) adj6 (function* or disfunction* or dysfunction* or impairment*)).tw,ot. 28 ((Semmes‐Weinstein monofilament or steel ball‐bearing or two‐point discriminator) adj6 test*).tw,ot. 29 (steel adj6 (ball‐bearing or ball bearing)).tw,ot. 30 ((sensor* or neuro*) adj3 (test* or devic*)).tw,ot. 31 (vibration* adj3 sensation*).tw,ot. 32 (vibratory adj3 perception*).tw,ot. 33 vibratometry.tw,ot. 34 (vibrotactile adj3 measurement*).tw,ot. 35 (nylon adj3 filament*).tw,ot. 36 (Frey* or neuropen or ipswich touch test* or IpTT).tw,ot. 37 (tactile adj3 (perception threshold* or sensation*)).tw,ot. 38 (pressure adj3 (sensation* or perception*)).tw,ot. 39 (tendon adj3 reflex*).tw,ot. 40 (ankle jerk or Achilles tendon reflex*).tw,ot. 41 or/14‐40 42 exp ankle/ or exp achilles tendon/ 43 exp reflex/ 44 42 and 43 45 41 or 44 46 13 and 45 47 limit 46 to humans

Web of Science: Science Citation Index Expanded

# 1 Topic=(peripheral nervous diseas*) OR Topic=(peripheral nervous disorder*) OR Topic=(polyneuropath*) OR Topic=(neuropath*) # 2 Topic=(diabet*) # 3 #2 AND #1 # 4 Topic=(quantitative sensory test*) OR Topic=(tactile circumferential discriminator) # 5 Topic=(biothesiometer) OR Topic=(neurothesiometer) OR Topic=(maxivibrometer) OR Topic=(vibrameter) OR Topic=(vibratron) OR Topic=(case IV system) # 6 Topic=(light touch perception*) OR Topic=(vibration perception*) # 7 Topic=(nerve conduction test*) OR Topic=(nerve conduction examination*) OR Topic=(nerve conduction stud*) # 8 Topic=(tuning fork*) # 9 Topic=(quantitative sensory test*) # 10 Topic=(vibration* threshold*) OR Topic=(perception* threshold*) # 11 Topic=(simple test*) # 12 Topic=(monofilament*) OR Topic=(vibration perception*) OR Topic=(ankle reflex*) # 13 Topic=(nerve conduction velocit*) OR Topic=(vibration test*) OR Topic=(SWMT) OR Topic=(VPT) OR Topic=(QST) OR Topic=(TCD) # 14 Topic=(latency diagnos*) OR Topic=(velocity diagnos*) OR Topic=(amplitude diagnos*) # 15 Topic=(large fiber function*) OR Topic=(large fiber disfunction*) OR Topic=(large fiber dysfunction*) OR Topic=(large fiber impairment*) # 16 Topic=(large fibre function*) OR Topic=(large fibre disfunction*) OR Topic=(large fibre dysfunction*) OR Topic=(large fibre impairment*) # 17 Topic=(Semmes‐Weinstein monofilament) OR Topic=(steel ball‐bearing) OR Topic=(two‐point discriminator test*) # 18 Topic=(vibration* sensation*) OR Topic=(vibratory perception*) OR Topic=(vibratometry) OR Topic=(vibrotactile measurement*) OR Topic=(nylon filament*) # 19 Topic=(Frey*) OR Topic=(neuropen) OR Topic=(ipswich touch test*) OR Topic=(IpTT) # 20 Topic=(tactile perception threshold*) OR Topic=(tactile sensation*) # 21 Topic=(pressure sensation*) OR Topic=(pressure perception*) # 22 Topic=(ankle reflex*) OR Topic=(tendon reflex*) # 23 Topic=(ankle jerk) OR Topic=(Achilles tendon reflex*) # 24 Topic=(sensor test*) OR Topic=(neuro test*) OR Topic=(sensor device*) OR Topic=(neuro device*) # 25 #24 OR #23 OR #22 OR #21 OR #20 OR #19 OR #18 OR #17 OR #16 OR #15 OR #14 OR #13 OR #12 OR #11 OR #10 OR #9 OR #8 OR #7 OR #6 OR #5 OR #4 # 26 #25 AND #3 # 27 Topic=(animal*) # 28 #26 NOT #27

MEDION

ICPCcode: "Neurological" or "Endocrine metabolic and nutritional" Filter: Systematic Reviews of Diagnostic Studies

ARIF

neuropath*

Trial registers

The metaRegister of Controlled Trials: diabetes and neuropathy The EU Clinical Trials register: neuropath* The US National Institutes of Health trials register ClinicalTrials.gov: "Diabetic Neuropathies"(by topics) The Australian New Zealand Clinical Trials Registry: neuropathy The WHO International Clinical Trials Registry Platform Search Portal: diabetes and neuropathy

Grey literature

neuropath*

'My NCBI' alert service

("diabetic neuropathies"[MeSH Terms] OR ("diabetic"[All Fields] AND "neuropathies"[All Fields]) OR "diabetic neuropathies"[All Fields] OR ("diabetic"[All Fields] AND "neuropathy"[All Fields]) OR "diabetic neuropathy"[All Fields]) AND ("diagnosis"[Subheading] OR "diagnosis"[All Fields] OR "screening"[All Fields] OR "mass screening"[MeSH Terms] OR ("mass"[All Fields] AND "screening"[All Fields]) OR ("early"[All Fields] AND "detection"[All Fields]))