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| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
|---|---|---|---|---|
| 1 Alignment rate (mm/8 weeks, Between first molars) | 1 | Mean Difference (IV, Fixed, 95% CI) | Totals not selected | |
| 2 Pain (VAS, day 1) | 2 | 127 | Mean Difference (IV, Fixed, 95% CI) | ‐2.68 [‐6.75, 1.38] |
| 3 Pain (VAS, day 7) | 2 | 127 | Mean Difference (IV, Fixed, 95% CI) | ‐0.37 [‐0.91, 0.17] |
