Doyle 1992.

Study characteristics
Methods	RCT
Participants	182 women undergoing Large Loop Excision of the Transformation Zone (LLETZ) of the cervix.
Interventions	Monsel's Solution applied to cervical wound. No extra treatment.
Outcomes	Discharge as measured subjectively by women on daily sanitary pad chart.
Notes	50 women failed to complete their follow‐up questionnaires excluded from analysis. 2 women had primary haemorrhages, 5 women were deemed to be unsuitable after randomisation. Assumed that randomisation is 1:1 so 63 randomised to Monsel's solution and 62 randomised to control, "it was calculated that by entering 60 patients into each arm of the study, there would be a greater than 85% chance of detecting a fall of 25% in the discharge score ...".
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not reported
Allocation concealment (selection bias)	Low risk	"The women were randomised ... by sealed opaque envelope to either the control or the Monsel's group".
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Not reported
Incomplete outcome data (attrition bias) All outcomes	High risk	For all outcomes: % analysed: 125/182 (69%)
Selective reporting (reporting bias)	Unclear risk	Insufficient information to permit judgement
Other bias	Unclear risk	Insufficient information to assess whether an important risk of bias exists