Grundsell 1984(b).

Study characteristics
Methods	RCT
Participants	220 women undergoing laser miniconization as an out‐patient procedure for mild/moderate dyskaryosis. All women had vasopressin injected into the cervix prior to treatment.
Interventions	Intravenous tranexamic acid during procedure and 1 g orally tds for 14 days
Outcomes	Primary and secondary haemorrhage
Notes	Citation duplicated to demonstrate two different study groups in analysis
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not reported, "patients were prospectively randomised into one group given tranexamic acid ... and another group not given antifibrinolytic therapy".
Allocation concealment (selection bias)	Unclear risk	Not reported
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Not reported
Incomplete outcome data (attrition bias) All outcomes	Low risk	For primary and secondary haemorrhage: % analysed: 220/220 (100%)
Selective reporting (reporting bias)	Unclear risk	Insufficient information to permit judgement
Other bias	Unclear risk	Patient baseline characteristics in the two groups were not reported so possibility of inexplicable differences between two groups.