Lee 1986.

Study characteristics
Methods	RCT
Participants	50 women undergoing laser vaporization
Interventions	Citanest (prilocaine with octapressin) No analgesia/ vasoconstrictor
Outcomes	Subjective grading of perioperative bleeding by operator
Notes	25 women randomised to Citanest 25 women randomised to no analgesia/ vasoconstrictor All patients were menopausal and aged between 19 and 39 years
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not reported, merely states, "study was a randomised comparison of two groups of 25 patients each ...".
Allocation concealment (selection bias)	Unclear risk	Not reported
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Not reported
Incomplete outcome data (attrition bias) All outcomes	Low risk	For troublesome bleeding: % analysed: 50/50 (100%)
Selective reporting (reporting bias)	Unclear risk	Insufficient information to permit judgement
Other bias	Unclear risk	Insufficient information to assess whether an important risk of bias exists