NCT02185196.
Trial name or title | Vitamin D supplementation: impact on severe pneumonia among under 5 children |
Methods | RCT |
Participants | Children of either sex aged 3 to 59 months, with a clinical diagnosis of severe pneumonia with or without diarrhoea |
Interventions | Vitamin D₃: 20,000 IU vitamin D₃ in children < 6 months; 50,000 IU in children 6 to 12 months; and 100,000 IU in children 13 to 59 months of age on first day and 10,000 IU for next 4 days Placebo: 20,000 IU Miglyol‐oil in children < 6 months; 50,000 IU in children 6 to 12 months; and 100,000 IU in children 13 to 59 months of age on first day and 10,000 IU for next 4 days |
Outcomes | Primary: time taken for recovery from severe pneumonia Secondary: duration of hospitalisation, time taken for normalisation of temperature and respiratory rate, time taken for recovery from chest indrawing, time taken for oxygen saturation, feeding, and mental status to normalise, proportion of study children who will develop new episodes of pneumonia during the follow‐up period |
Starting date | June 2014 |
Contact information | Fahmida Chowdhury, International Centre for Diarrhoeal Disease Research, Bangladesh, fahmida_chow@icddrb.org |
Notes | ClinicalTrials.gov identifier: NCT02185196 |
RCT: randomised controlled trial