Skip to main content
. 2018 Jul 19;2018(7):CD011597. doi: 10.1002/14651858.CD011597.pub2

NCT02185196.

Trial name or title Vitamin D supplementation: impact on severe pneumonia among under 5 children
Methods RCT
Participants Children of either sex aged 3 to 59 months, with a clinical diagnosis of severe pneumonia with or without diarrhoea
Interventions Vitamin D₃: 20,000 IU vitamin D₃ in children < 6 months; 50,000 IU in children 6 to 12 months; and 100,000 IU in children 13 to 59 months of age on first day and 10,000 IU for next 4 days
Placebo: 20,000 IU Miglyol‐oil in children < 6 months; 50,000 IU in children 6 to 12 months; and 100,000 IU in children 13 to 59 months of age on first day and 10,000 IU for next 4 days
Outcomes Primary: time taken for recovery from severe pneumonia
Secondary: duration of hospitalisation, time taken for normalisation of temperature and respiratory rate, time taken for recovery from chest indrawing, time taken for oxygen saturation, feeding, and mental status to normalise, proportion of study children who will develop new episodes of pneumonia during the follow‐up period
Starting date June 2014
Contact information Fahmida Chowdhury, International Centre for Diarrhoeal Disease Research, Bangladesh, fahmida_chow@icddrb.org
Notes ClinicalTrials.gov identifier: NCT02185196

RCT: randomised controlled trial