(A) Higher TEER of the MDC-, filipin-, EIPA- or RGDS-treated cell monolayers during incubation or infection with L. interrogans for the indicated times, detected using a cell electric resistance indicator. (B) Higher TEER of the Rab11-, Sec15-, Sec3-, VAMP2- or SYN1-depleted cell monolayers during incubation or infection with L. interrogans for the indicated times, detected using a cell electric resistance indicator. (C) Higher TEER of the LF + PA or BoNT/D-LC-treated cell monolayers during incubation or infection with L. interrogans for the indicated times, detected using a cell electric resistance indicator. (D) Lower TEER of the LY294002-, 14/Y15-, Cyto-D, COL-, EF + PA or BoNT/C-LC-pretreated cell monolayers, detected using a cell electric resistance indicator.