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. 2018 Sep 27;2018(9):CD001506. doi: 10.1002/14651858.CD001506.pub4

Palacio 2014.

Methods Open‐label RCT.
Design: parallel group.
Location: 2 centres in Argentina.
Duration: 24 weeks.
Participants 27 children aged 3 to 6 years with CF. 21 completed trial.
Interventions Intervention 1: HS 7% nebulised 2x daily.
Control: IS 0.9%, nebulised 2x daily.
Salbutamol given prior to each dose.
Outcomes Primary outcome
Lung function.
Secondary outcomes
Respiratory symptoms.
Anthropometric measures.
New isolation of Pseudomonas aeruginosa.
Rate of exacerbations.
AEs.
Adherence.
Notes We are waiting for further data to judge whether this should be included.