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. 2018 Jul 5;2018(7):CD012960. doi: 10.1002/14651858.CD012960.pub2

14. Results of cohort studies: blood pressure.

Study ID;
mean age at baseline;
analysis
Outcome Outcome units Time point (year) Exposure Exposure unit Results of association (all reported values) Direction;a
energy intake adjusted (yes/no)
Matched groups or adjusted for (or both)
SBP at > 1to 2 years: 1 cohort study; 1 analysis (n = 310) in boys and girls aged 13 years
Setayeshgar 2017
12.5 years;
regression
SBP z‐score 2 Total fat intake (single 24‐hour recall at baseline) per 10 g n overall = 310; regression result.
β = 0.03 (95% CI 0.00004 to 0.06), P < 0.05.
After 2 years, for every 10 g increase in total fat intake, SBP will increase by 0.03 z‐score
+
No
Adjusted for baseline BMI z‐score, baseline SBP and DBP, moderate to vigorous physical activity, vegetables and fruit, fibre, milk, sodium and added sugar.
SBP at > 2to 5 years: 1 cohort study; 1 analysis (n = NR) in boys and girls aged 10 years
Obarzanek 1997 (cohort)
9.6 years; regression
SBP mmHg 3 Total fat intake (multiple 24‐hour recalls at baseline, 1 and 3 years) g n overall = NR; regression result.
B = 0.4, P < 0.1.
After 3 years, for every 1 g increase in total fat intake, SBP will increase by 0.4 mmHg
+
Yes
Adjusted for height, weight and gender, with all sources of calories in the model.
DBP at > 1to 2 years: 1 cohort study; 1 analysis (n = 310) in boys and girls aged 13 years
Setayeshgar 2017
12.5 years;
regression
DBP z‐score 2 Total fat intake (single 24‐hour recall at baseline) per 10 g n overall = 310.
β = 0.03 (95% CI 0.003 to 0.05), P < 0.05.
After 2 years, for every 10 g increase in total fat intake, DBP will increase by 0.03 z‐scores
+
No
Adjusted for baseline BMI z‐score, baseline SBP and DBP, moderate to vigorous physical activity, vegetables and fruit, fibre, milk, sodium and added sugar.
DBP at > 2to 5 years: 1 cohort study; 1 analysis (n = NR) in boys and girls aged 10 years
Obarzanek 1997 (cohort)
9.6 years; regression
DBP mmHg 3 Total fat intake (multiple 24‐hour recalls at baseline, 1 and 3 years) g n overall = NR.
B = 0.43, 0.01 < P < 0.06.
After 3 years, for every 1 g increase in total fat intake, DBP will increase by 0.43 mmHg
+
Yes
Adjusted for height, weight and gender, with all sources of calories in the model.

aDirection refers to whether there was a positive (+: exposure and outcome moved in the same direction), inverse/negative (‐: exposure and outcome moved in opposite directions) or zero (0: no association) between total fat intake and the outcome.

B: unstandardised beta coefficient; β: standardised beta‐coefficient; BMI: body mass index; CI: confidence interval; DBP: diastolic blood pressure; NR: not reported; SBP: systolic blood pressure.