Frankova 2013.

Methods	Prospective cohort study Setting: not reported Country: Czech Republic Duration of follow‐up: 6 weeks Treatments: gauze hydrogen calcium salts of oxidised cellulose
Participants	20 participants with VLU and other wounds (VLU 15, A‐V leg ulcers 3, decubitus ulcer 1, trophic leg ulcer 1) Median age: 65.7 (SD 7.1) years Sex (M:F): 10:10
Prognostic factors	MMP‐2 and MMP‐9 (continuous data); total MMP (pro‐, active‐ and TIMP complexed) median (IQR assumed) reported but not linked to outcome. Measurement method sandwich ELISA Time of measurement: baseline and every 2 weeks Wound fluid sampling method: entrapment in dressings
Notes	Minimal data collection; no results. Risk of bias assessments available on request