NCT02128191

Trial name or title	No treatment versus ibuprofen treatment for patent ductus arteriosus in preterm infants
Methods	Randomised controlled trial
Participants	Infants with a gestational age of ≤ 30 weeks or birth weight of ≤ 1250 grams confirmed to have haemodynamically significant PDA during day of life 7 to 14
Interventions	Ibuprofen: initial dose of oral ibuprofen 10 mg/kg, followed by 2 doses of 5 mg/kg 24 and 48 hours later Saline: normal saline followed by second and third dose 24 and 48 hours later, at equal volume to ibuprofen
Outcomes	Incidence of moderate‐to‐severe bronchopulmonary dysplasia or mortality at 36 weeks' PMA (time frame 36 weeks' PMA)
Starting date	July 2014
Contact information	Contact: Se In Sung, M.D.; phone: 82‐2‐3410‐1775; sein.sung@samsung.com
Notes	ClinicalTrials.gov Identifier: NCT02128191 As of October 14, 2016, this study was still recruiting