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. 2018 Jul 9;2018(7):CD011151. doi: 10.1002/14651858.CD011151.pub3

4.

4

Mortality.

Duval and Tweedie's trim and fill analysis.

Actual results displayed in blue. Results corrected for the possibility of a publication bias displayed in red.

The impact of asymmetry in the funnel plot led to a trim and fill estimate that would not change the conclusion, that is, there would still not be a difference for mortality between the two interventions (red lozenge).