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. 2018 Jul 9;2018(7):CD011151. doi: 10.1002/14651858.CD011151.pub3

2. Additional information on the included studies.

Study Criteria for extubation ICU ventilation Criteria for non‐invasive ventilation Criteria for invasive ventilation
Bates 2015 Once participants were titrated down to an FiO2 ≤ 0.5 and PEEP 5 cmH2O, they were assessed twice daily with spontaneous breathing trials.
Participants were considered ready for extubation from a pulmonary mechanics standpoint if their rapid shallow breathing index was < 105 for 30 minutes.
Same parameters for the first 3 after surgery if required Unspecified All participants admitted to ICU and kept on mechanical ventilation through an endotracheal tube after surgery
Chaney 2000 Normal ICU protocol: appropriate sensorium, normothermia, haemodynamic stability, adequate pulmonary function (PaO2 > 60 mmHg with FiO2 0.4), adequate urine output and minimal chest tube output Same mode of ventilation for the first hour after surgery, then tidal volume 8 mL/kg, rate 10/minute, FiO2 1.0 and PEEP 5 cmH2O for all participants Unspecified Unspecified
Choi 2006 Unspecified If the surgical procedure exceeded 5 hours, anaesthesiologists were allowed to change the ventilation strategy thereafter Unspecified Unspecified
Chugh 2012 Unspecified Unspecified Unspecified Unspecified
Fernandez‐Bustamante 2014 Unspecified Unspecified Unspecified Unspecified
Futier 2013 Recovery of a spontaneous ventilation with an expired tidal volume 5–8 mL/kg, respiratory rate 12–25 breaths/min, absence of residual neuromuscular blockade (assessed by a T4/T1 ratio ≥ 90%), peripheral oxygen saturation ≥ 95%, stable haemodynamics and body temperature ≥ 36°C Unspecified Unspecified Unspecified
Ge 2013 Unspecified Unspecified Unspecified Unspecified
Koner 2004 Unspecified Unspecified Unspecified Unspecified
Kuzkov 2016 The criteria for discontinuation of respiratory support
 were as follows: the ability to tolerate 30 minutes of spontaneous breathing trial via the pressure support ventilation with pressure support level of 6–8 cmH2O, PaO2/FiO2 > 200 mmHg, spontaneous minute volume < 10 L/min, and respiratory rate < 30/minute (frequency/tidal volume < 65 1/L and tidal volume > 6 mL/kg predicted body weight) as well as normal body
 temperature, no obvious bleeding or anaemia, haemodynamic stability and adequate analgesia Unspecified Unspecified Unspecified
Memtsoudis 2012 Unspecified Unspecified Unspecified Unspecified
Park 2016a Unspecified None of the participants required postoperative ventilatory assistance Unspecified Unspecified
Sato 2016 Unspecified All participants were extubated in the operating room and were spontaneously breathing when they arrived at the postanaesthesia care unit Unspecified Unspecified
Shen 2015 Unspecified Unspecified Unspecified Unspecified
Soh 2018 Unspecified Unspecified Unspecified Unspecified
Sundar 2011 Awake status (Riker Sedation‐Agitation Scale score of 3 or 4), haemodynamic stability (minimal doses of nitroglycerine or phenylephrine), and adequate gas exchange (PaCO2 100 mmHg, FiO2 0.4, PEEP 5 cmH2O)
 Participants were then placed in protocol sequence; they were placed on pressure support ventilation, assessed using the rapid shallow breathing index on PEEP, receiving pressure support levels of 5 cmH2O, followed by a spontaneous breathing trial of 30 min. Participants who passed this sequence
 were then extubated Study ventilator settings were applied immediately after induction of general anaesthesia and continued throughout surgery and the subsequent ICU stay Unspecified Unspecified
Treschan 2012 Unspecified Mechanical ventilation of participants who were transferred intubated to the ICU was continued according to group assignment under the discretion of the
 intensivist in charge Unspecified Unspecified
Weingarten 2010 Unspecified Unspecified Unspecified Unspecified
Xiong 2016 Unspecified Unspecified Unspecified Unspecified
Zupancich 2005 Participants were extubated when haemodynamically stable, fully rewarmed, awake, without surgical bleeding and with optimal blood gases After chest closure, participants were transferred to the ICU and ventilated, with the ventilatory pattern selected randomly Unspecified Unspecified

Prophylactic use of non‐invasive ventilatory support was not mentioned in any of the studies.

cmH2O: centimetres of water; FiO2: inspired fraction of oxygen; ICU: intensive care unit; min: minute; mL/kg: millilitre per kilogram of body weight; mmHg: millilitre of mercury; n: number of participants; PaCO2: arterial partial pressure in carbon dioxide; PaO2: arterial partial pressure in oxygen; PEEP: positive end‐expiratory pressure.