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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Basic Clin Pharmacol Toxicol. 2019 Jan 10;124(6):670–680. doi: 10.1111/bcpt.13194

Figure 3. STV downregulates TGF-β1 in fibrotic livers.

Figure 3.

Immunohistochemistry TGF-β1 obtained from livers of control rats (A); TAA-treated rats (B); STV+TAA-treated rats (C) and rats administered with STV alone (D). Histogram depicts the percentage of positivity TGF-β1 obtained from immunohistochemistry slices (E). Increase in relative mRNA expression of TGF-β1 (F) is shown. Protein expression level of TGF-β1 was measured by western blot from liver slices (G). β-actin was used as a control. The values are expressed as a fold increase of optical densitometry normalized to the control group values (control = 1). Each bar represents the mean value of experiments conducted in duplicate assays ± SEM (n = 3). ap < 0.05 vs control. bp < 0.05 vs TAA.