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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Clin Pharmacol Ther. 2019 Feb 10;105(6):1462–1470. doi: 10.1002/cpt.1332

Figure 2.

Figure 2

Overall performance of clearance (CL) prediction for drugs 60–80% renally eliminated in newborns and infants using a postmenstrual age (PMA)-based model. The circles represent patients with gestational age ≥ 37 weeks, and the triangles represent patients with gestational age < 37 weeks. The colors of red, blue, and dark green represent < 37 weeks PMA, 37 to < 42 weeks PMA, and ≥ 42 weeks PMA, respectively. The dotted lines represent 0.5 and twofold for the ratio of model-predicted relative to the observed value.