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. Author manuscript; available in PMC: 2019 May 13.
Published in final edited form as: Cytotherapy. 2019 Mar 14;21(5):546–560. doi: 10.1016/j.jcyt.2018.12.005

Figure 2.

Figure 2

Histological evaluation of the persistence of human cells in the lungs of NSG mice treated with three bi-weekly intravenous injections of 2 × 106 ABCB5+ MSCs/mouse. Mice were sacrificed at 13 weeks after the first MSC injection. Tissues were stained with anti-mitochondrial antibody (AMA) (brown) as a marker of human-origin cells. (Left) Skin at the injection site of a mice injected subcutaneously with 1.08 × 106 HeLa cells served as positive control. (Middle and Right) Representative microphotographs of lung sections of MSC-treated mice in which AMA staining was exceptionally rare. Scale bars: 50 μm.