Table IV.
Vehicle | 2 × 106 MSCs/animal | |
---|---|---|
Males | n = 10 | n = 9 |
Hematology | ||
Hematocrit, L/L | 0.459 (0.0257) | 0.476 (0.0144) |
Hemoglobin, g/dL | 12.6 (0.63) | 13.0 (0.27) |
White blood cells,9× 109/L | 0.81 (0.207) | 1.10 (0.574) |
Neutrophils, × 10 /L | 0.53 (0.153) | 0.65 (0.233) |
Lymphocytes, × 109/L | 0.22 (0.126) | 0.33 (0.357) |
Monocytes, × 10 9/L | 0.04 (0.023) | 0.09 (0.039)** |
Eosinophils, × 10 /L | 0.02 (0.010) | 0.03 (0.011) |
Clinical chemistry | ||
AST, U/L | 45 (9.7) | 43 (7.9) |
ALP, U/L | 46 (3.1) | 45 (2.8) |
Urea, mmol/L | 8.56 (0.741) | 7.72 (0.433)* |
Cholesterol, mmol/L | 2.63 (0.127) | 2.38 (0.240)* |
Triglycerides, mmol/L | 1.02 (0.273) | 0.61 (0.194)** |
Glucose, mmol/L | 14.09 (1.271) | 15.82 (2.533) |
Na+, mmol/L | 152 (1.2) | 152 (2.2) |
K+, mmol/L | 4.3 (0.41) | 4.4 (0.32) |
Ca2+, mmol/L | 2.39 (0.045) | 2.34 (0.072)* |
Albumin, g/L | 31 (1.1) | 29 (0.8)** |
Total protein, g/L | 49 (1.3) | 46 (1.5)** |
Females | n = 10 | n = 10 |
Hematology | ||
Hematocrit, l/L | 0.490 (0.0096) | 0.478 (0.0154)* |
Hemoglobin, g/dL | 13.6 (0.38) | 13.5 (0.43) |
White blood cells,9× 109/L | 0.93 (0.256) | 0.80 (0.256) |
Neutrophils, × 10 /L | 0.62 (0.153) | 0.55 (0.164) |
Lymphocytes, × 109/L | 0.23 (0.140) | 0.18 (0.137) |
Monocytes, × 10 9/L | 0.06 (0.038) | 0.05 (0.016) |
Eosinophils, × 10 /L | 0.02 (0.013) | 0.02 (0.010) |
Clinical chemistry | ||
AST, U/L | 48 (10.8) | 43 (8.3) |
ALP, U/L | 77 (8.1) | 73 (6.0) |
Urea, mmol/L | 7.37 (0.619) | 6.83 (0.483) |
Cholesterol, mmol/L | 1.94 (0.143) | 1.81 (0.151) |
Triglycerides, mmol/L | 0.63 (0.271) | 0.42 (0.220) |
Glucose | 15.09 (1.147) | 11.93 (1.829)** |
Na+, mmol/L | 151 (1.3) | 151 (2.9)** |
K+, mmol/L | 3.7 (0.30) | 4.0 (0.29)* |
Ca2+, mmol/L | 2.39 (0.046) | 2.34 (0.055)* |
Albumin, g/L | 31 (0.6) | 31 (1.1) |
Total protein, g/L | 46 (1.2) | 46 (1.3) |
Animals were followed up for 13 weeks. Values are means (SD)
p<0.05
p<0.01 vs. vehicle group, t-test on log-transformed data (hematology) or t-test or Wilcoxon test (clinical chemistry), as appropriate.