2.

Eleven-year ESCC and all-cause incidence and mortality rates in SD/CIS patients in Linzhou

Groups	Cumulative incidence								Cumulative mortality
	ESCC				All-cause				ESCC				All-cause
	n	Rate (%)* (95% CI)	P**		n	Rate (%)* (95% CI)	P**		n	Rate (%)* (95% CI)	P**		n	Rate (%)* (95% CI)	P**
ESCC, esophageal squamous cell carcinoma; SD/CIS, severe dysplasia/carcinoma in situ; 95% CI, 95% confidence interval; *, education, family members and family history of cancer were adjusted for the cumulative incidence and mortality; **, χ2 test was used to compare the rates between the two groups. SD/CIS patients were divided into two groups by whether they received endoscopic treatments (EMR, MBM or ESD). EMR, endoscopic mucosal resection; MBM, multiband mucosectomy; ESD, endoscopic submucosal dissection.
Untreated group (n=78)	8	10.7 (6.9−16.1)	0.006		20	28.1 (22.0−35.2)	<0.001		1	0.7 (0.2−3.4)	0.938		10	13.1 (8.9−18.9)	<0.001
Treated group (n=97)	3	3.2 (1.4−7.0)			10	11.3 (7.4−16.9)			1	0.8 (0.2−3.5)			3	2.3 (0.9−5.8)