2.

Impact of different factors on PFS before RFA treatment for HCC

Variables	β	SE	Wald value	HR	95% CI	P
The Cox model of univariate analysis, n=64, α=0.05. PFS, progression-free survival; RFA, radiofrequency ablation; HCC, hepatocellular carcinoma; MTD, maximal tumor diameter; AFP, alpha-fetoprotein; TFN, transferrin; ADC, apparent diffusion coefficient; RADC, non-lesion area ADC; β, regression coefficient; SE, standard error; HR, hazard ratio; 95% CI, 95% confidence interval. *, ADC values are in units of 10−3 mm2/s.
Gender	−0.53	0.43	1.54	0.59	0.25−1.36	0.22
Age (year)	−0.04	0.02	2.90	0.97	0.93−1.01	0.09
MTD (cm)	−0.07	0.14	0.23	0.94	0.72−1.23	0.64
AFP (ng/mL)	0	0	0.92	1.00	1.00−1.01	0.34
TFN (ng/mL)	0	0	0.32	1.00	0.99−1.03	0.57
ADC10	0	0	2.79	1.00	1.00−1.01	0.09
ADC30	0	0	2.29	1.00	0.97−1.02	0.13
ADCmedian	0	0	1.92	1.00	0.98−1.01	0.17
ADCmax	0	0	0.77	1.00	0.99−1.02	0.38
RADC10	3.44	1.78	3.73	31.02	1.01−101.32	0.04*
RADC30	3.78	1.91	3.91	43.84	1.03−185.90	0.04*
RADCmedian	3.79	1.91	3.92	44.29	1.04−198.74	0.04*
RADCmax	2.93	1.92	2.34	18.72	0.44−80.11	0.13