6.
Variables of multiple-use models
| Variables | Bach | Spitz
(2007) |
Spitz
(2008) |
LLP | LLPi | PLCO
(2009) |
PLCO
(2011) |
PLCOM2012 | Etzel | Pittsburgh | Hoggart |
| BMI, body mass index; COPD, chronic obstructive pulmonary disease; LLP, Liverpool Lung Project; PLCO, the Prostate, Lung, Colorectal and Ovarian; Y, the variable was included in the model. | |||||||||||
| Sociodemographic factors | |||||||||||
| Age | Y | Y | Y | Y | Y | Y | |||||
| Gender | Y | Y | Y | Y | |||||||
| Race or ethnic group | Y | ||||||||||
| Education | Y | Y | Y | Y | |||||||
| BMI | Y | Y | Y | Y | |||||||
| Exposure history | |||||||||||
| Dust exposures | Y | Y | Y | Y | |||||||
| Asbestos exposure | Y | Y | Y | Y | Y | ||||||
| Environmental tobacco | |||||||||||
| Smoke exposure | Y | ||||||||||
| Smoking history | |||||||||||
| Age stopped smoking | Y | Y | |||||||||
| Smoking duration | Y | Y | Y | Y | Y | Y | |||||
| Pack-years smoked | Y | Y | Y | Y | |||||||
| Smoking status | Y | Y | Y | ||||||||
| Smoking intensity | Y | Y | |||||||||
| Smoking quit time | Y | Y | |||||||||
| Cigarettes per day | Y | ||||||||||
| Time since smoking cessation | Y | ||||||||||
| Medical history | |||||||||||
| Emphysema | Y | Y | |||||||||
| Hay fever | Y | Y | Y | Y | |||||||
| Bleomycin sensitivity | Y | ||||||||||
| Prior diagnosis of pneumonia | Y | ||||||||||
| Prior diagnosis of malignant
tumor |
Y | Y | |||||||||
| COPD | Y | Y | Y | Y | |||||||
| Chest X-ray in past 3 years | Y | ||||||||||
| Personal history of cancer | Y | ||||||||||
| Asthma | Y | ||||||||||
| Family history | |||||||||||
| Family history of cancer | Y | Y | Y | ||||||||
| First-degree relatives with
cancer |
Y | ||||||||||
| Family history of lung cancer | Y | Y | Y | Y | Y | ||||||
| Nodule | Y | ||||||||||
| Family history of smoking-
related cancer |
Y | ||||||||||
| Genetic risk factors | |||||||||||
| DNA repair capacity | Y | ||||||||||
| chr15q25 | Y | ||||||||||
| chr5p15 | Y | ||||||||||