Table 1: commonly studied PSs and their photodynamic properties, *: Enterohemorrhagic E. coli.
class | example | charge | Excitation maximum | Sample (bacteria) | Concentration of PS | Overall efficacy | Ref |
---|---|---|---|---|---|---|---|
Phenothiazinium | Methylene blue | cationic | 632nm | Dental plaque samples | 25 µg/ml | 8% | (11) |
Toluidine blue | cationic | 410nm | S. mutans | 100 mg/l | 2–5 log10 | (77, 78) | |
E. coli | 35 µM | 0.08 log10 | |||||
Rose Bengal | anionic | 532nm | E. faecalis | 10 µM | 4 log10 | (79) | |
P. aeruginosa | 3 log10 | ||||||
Dimethyl methylene blue | cationic | 635–652nm | A. baumannii | 200 µM | 2 log10 | (80, 81) | |
New methylene blue | cationic | 635–652nm | A. baumannii | 800 µM | 3.2 log10 | (80, 81) | |
Natural PSs | Curcumin | neutral | 547nm | S. mutans | 0.75 to 5 g/l | ≤ 3 log10 | (41, 42) |
L. acidophilus | |||||||
Hypericin | neutral | 593nm | S. aureus | 100 nM | 4–5 log10 | (82–84) | |
E. coli | 1 µg/ml | ≤ 0.2 log10 | |||||
Flavin derivatives | cationic | 450nm | MRSA | 50 µM | 5.1 log10 | (85) | |
EHEC* | 50 µM | 6.5 log10 | |||||
Tetra-pyrrole structures | Porphyrin | cationic | 446nm | S. aureus | 10 µM | 1–2 log10 | (32, 86, 87) |
P. aeruginosa | 225 µM | 4 log10 | |||||
E. faecalis | 100 µM | No effect | |||||
Phthalocyanine | Neutral | 670nm | A. hidrophila | 2 mM | ≤ 0.5 log10 | (22) | |
Zink Pc derivatives | Cationic | 690 nm | S. aureus | 64 ng/ml | 5–6 log10 | (88–90) | |
P. aeruginosa | 26 µg/ml | 5–6 log10 | |||||
Chlorine | Neutral | 660nm | S. aureus | 10 µg/ml | 5 log10 | (91) | |
E. coli | 5 µg/ml | 0.75 log10 | |||||
Chlorine | Cationic | 532nm | E. coli | 5 µg/ml | 0.77 log10 | (92) | |
Nano structures | Fullerenes | neutral | 532nm | S. aureus | 1 µg/ml | 3 log10 | (93, 94) |
E. coli | ≤ 85% | ||||||
Titanium dioxide | neutral | near-UV light (400) | Water treatment | 1 mg/ml | 77–93% | (95) |