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. 2019 May 7;13:94. doi: 10.3389/fnbeh.2019.00094

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Copyright © 2019 Schleicher, Ott, Müller, Silcher, Sichler, Löw, Wagner and Bouter.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Altered prepulse inhibition (PPI) in CBD-treated C57BL/6J mice. Former (A) and current (D) CBD-treated C57BL/6J mice showed an unaltered acoustic startle response (ASR) and latency to startle (B,E). PPI (PPI%) was unaltered in former CBD-treated C57BL/6J (C). PPI was significantly altered in current treated CBD C57BL/6J mice at 75 dB and 80 dB (F). Two-way ANOVA, n = 12–15, **p < 0.01. Data presented as mean ± SEM.