Table 3.
Adverse events (AEs) by system organ classa
| Body system AE, n (%) of patients with ≥ 1 | Baseline biologic experience | All patients n = 1912 | |
|---|---|---|---|
| Biologic naïve n = 1073 | Biologic exposed n = 839 | ||
| Infections and infestations | 90 (8.4) | 175 (20.9) | 265 (13.9) |
| Investigations | 118 (11.0) | 98 (11.7) | 216 (11.3) |
| Musculoskeletal and connective tissue disorders | 44 (4.1) | 77 (9.2) | 121 (6.3) |
| Gastrointestinal disorders | 42 (3.9) | 70 (8.3) | 112 (5.9) |
| Skin and subcutaneous tissue disorders | 41 (3.8) | 66 (7.9) | 107 (5.6) |
| Blood and lymphatic system disorders | 54 (5.0) | 51 (6.1) | 105 (5.5) |
| All body systems | 367 (34.2) | 450 (53.6) | 817 (42.7) |
aReported in ≥ 5% of all patients