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. 2019 May 13;9:7273. doi: 10.1038/s41598-019-43799-y

Table 2.

Mean (SD) of each group, mean (SD) difference within each group, and mean (95% CI) difference between groups.

Outcome Groups Differences Within Groups Difference Between Groups
Week 0 Week 1 Week 4 Week 1 minus Week 0 Week 4 minus Week 0 MFR minus Sham
MFR Sham MFR Sham MFR Sham MFR Sham MFR Sham Week 0 Week 1 Week 4
RDQ (0–5) 2.3
(1.0)
1.8
(1.0)
0.6
(0.6)
1.6
(0.8)
0.6
(0.5)
1.7
(1.0)
−1.7
(0.7)
−0.2
(0.7)
−1.6
(0.8)
−0.1
(0.6)
0.5
(−0.2 to 1.2)
−1.0**
(−1.5 to −0.5)
−1.1**
(−1.7 to −0.5)
GIQLI (0–144) 102.3
(19.0)
94.3
(20.9)
112.7
(13.2)
103.3
(22.7)
116.3
(14.6)
98.1
(20.7)
10.3
(8.2)
9
(18.1)
13.9
(12.8)
3.8
(8.7)
8.0
(−7.0 to 23.0)
9.3
(−4.5 to 23.2)
18.1*
(4.8 to 31.5)
PPI (mg/week) 88
(78)
135
(120)
36
(52)
132
(122)
33
(51)
131
(112)
−52
(49)
−3
(10)
−55
(55)
−4
(43)
−47
(−122 to 29)
−96*
(−166 to −26)
−97*
(−162 to −32)

MFR = myofascial release group, Sham = sham group, RDQ = Reflux Disease questionnaire; GIQLI = Gastrointestinal Quality of Life Index, PPI = Proton Pump Inhibitors.

P-values were obtained from two-way ANOVA tests: **p ≤ 0.001, *p ≤ 0.01.