Table 8.
Effect of Iranian propolis on level of hsCRP and cytokines in T2DM patients after 90 days.
| Variables | Propolis(n = 50) | Placebo(n = 44) | P-Valuea | ||
|---|---|---|---|---|---|
| Before | After | Before | After | ||
| hs-CRP, pg/ml | 3589.74 ± ± 25.20.96 | 3024.12 ± 2368.5 | 3925.92 ± 2546.47 | 6033.02 ± 2350.87b | 0.001 |
| TNF, pg/ml | 122.98 ± 115.44 | 85.69 ± 84.7b | 130.24 ± 11.99 | 146.41 ± 141.03b | 0.000 |
| IL6, pg/ml | 32.88 ± 44.61 | 24.4 ± 23.68 | 23.05 ± 22.03 | 27.02 ± 23.82 | 0.405 |
| IL1B, pg/ml | 34.84 ± 32.74 | 29.3 ± 25.66b | 23.72 ± 13.42 | 25.27 ± 14.25 | 0.373 |
aComparison of change between placebo and Iranian propolis values after 90 days. bP < 0.05 for baseline versus after 90 days within the group. Data are mean ± standard deviation. TNF-α, tumor necrosis factor-α; hs-CRP, high sensitivity C-reactive protein; IL-1β, interleukin-1β; IL-6, interleukin-6.