. 2019 May 13;9:7260. doi: 10.1038/s41598-019-43677-7

Table 1.

Electrophysiological characteristics of K_V4.3/DREAM wt, K_V4.3/DREAM Y118A and K_V4.3/DREAM Y130A.

DREAM	E_h,Act (mV)	s_Act (mV)	E_h,Inact (mV)	s_Inact (mV)	τ_Act (ms)	τ_Inact (ms)	τ_Rec (ms)
wt	1.1 ± 1.6	16.3 ± 0.2	−34.6 ± 1.7	4.6 ± 0.2	0.66 ± 0.05	45.1 ± 3.7	44.4 ± 3.8
Y118A	−4.3 ± 1.3***	16.7 ± 0.3	−36.3 ± 1.7	4.8 ± 0.1	0.80 ± 0.04*	90.4 ± 4.1***	57.9 ± 4.7*
Y130A	2.2 ± 1.3	16.7 ± 0.3	−26.7 ± 1.1**	4.8 ± 0.1	0.87 ± 0.05*	63.3 ± 3.7***	61.6 ± 5.3**

E_h,Act: Midpoint of the activation curve, s_Act: Slope of the activation curve, E_h,Inact: Midpoint of the inactivation curve, s_Inact: Slope of the inactivation curve, τ_Act: Activation time constant, τ_Inact: Inactivation time constant, τ_Rec: Time constant of recovery from inactivation.

*p < 0.05 vs K_V4.3/DREAM wt, **p < 0.01 vs K_V4.3/DREAM wt, ***p < 0.001 vs K_V4.3/DREAM wt of n = 18, 30 (DREAM Y118A) and 23 (DREAM Y130A) experiments.