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. 2019 Feb 20;8(2):155–175. doi: 10.1007/s40123-019-0170-1

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© The Author(s) 2019

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Non-proliferative and proliferative phases of MacTel. 1: A 34-year-old male with bilateral progressive visual loss. Fundus photo of the right eye showed temporal parafoveal foci of retinal pigment epithelium (RPE) hyperplasia with foveal pigmentary change (a). Corresponding OCT demonstrated outer retinal layer atrophy and outward configuration of the inner retinal layers while the RPE layer appeared to be intact (b). 2: A 41-year-old male, a known case of MacTel with acute onset of vision loss in the left eye. Fundus photo and OCT imaging of the left eye showed not only RPE hyperplasia and pigmentary changes but also retinal and sub-retinal hemorrhages due to RPE disruption and choroidal neovascularization (c, d). Images courtesy of Dr. Hamid Riazi