Table 1.
Demographics of study populations: aPL patients with definite APS, extended APS and non-APS.
| Definite APS | Extended APS | Non-APS | p* | |
|---|---|---|---|---|
| n (%) | 184 (35.1) | 175 (33.3) | 166 (31.6) | |
| Sex, F/M (ratio) | 147/37 (4.20:1) | 152/23 (6.61:1) | 145/21 (6.90:1) | 0.099 |
| Age ± SD; years old | 44.40 ± 12.54 | 46.82 ± 13.09 | 43.78 ± 13.19 | 0.071 |
| Race: White/Black/Others,||n (% in each group) | 81/24/79 (44.0/13.0/42.9) | 67/27/81 (38.3/15.4/46.3) | 80/23/63 (48.2/13.9/38.0) | 0.44 |
| BMI | 28.66 ± 6.86 | 28.94 ± 7.58 | 28.22 ± 6.57 | 0.64 |
| Thrombosis, Y/N, n (%) | 154/30 (83.7) | 83/92 (47.4) | 0/166 (0) | 1.4 × 10−69 |
| Pregnancy loss, female, Y/N, n (%) | 80/67 (54.4) | 26/126 (17.1) | 0/166 (0) | 1.7 × 10 −32 |
| SLE, Y/N, n (%) | 89/95 (48.4) | 99/76 (56.6) | 105/61 (63.3) | 0.019 |
| Complement C3 ± SD; mg/dL | 124.1 ± 36.0 | 128.4 ± 37.8 | 118.8 ± 33.4 | 0.048 |
| Complement C4 ± SD; mg/dL | 22.9 ± 10.9 | 20.0 ± 9.2 | 16.6 ± 8.8 | 2.6 × 10−8 |
| Correlations between C3 and C4, r2 | 0.217 (p = 3.0 × 10−11) | 0.310 (p = 2.7 × 10−15) | 0.321 (p = 4.0 × 10−15) |
r, coefficient of correlation.
*
p values obtained by χ2 analyses for categorical data, or by ANOVA (analysis of variance) for continuous data; ||others: other racial and multi-racial groups; p- < 0.05 are in bold fonts.