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. 2019 May 7;10:928. doi: 10.3389/fimmu.2019.00928

Figure 1.

Figure 1

Microbiota exposure decreases pathogen adherence to intestinal epithelial cells. (A) C. rodentium colony forming units (CFUs) in stool of infected germ-free (GF) and conventionally-housed (CNV) mice during early course of infection (day 4–6). Data are representative of at least 3 independent experiments with 3–4 mice per group. (B) Relative RegIIIγ mRNA expression in IECs isolated from the large intestine of GF and CNV mice compared to intestinal organoid cultures. (C) MFI of GFP-C. rodentium infected intestinal organoids derived from GF and CNV mice. Data represent two independent experiments with 3–4 mice per group. Results are mean ± SEM. *p < 0.05, ***p < 0.001.