Figure 5.

The effect of both low-dose and high-dose rapamycin on one pair of ASD LCLs. LCLs were exposed to low dose (0.01 nM and 0.1 nM) or high dose (1 nM and 10 nM) for either 1 h or 2 h followed by the Seahorse assay. For presentation purposes, both low doses at both time points were combined into one average data point and both high doses at both time points were combined into one data point. Standard error bars are also shown. Respiratory parameters including (A) ATP Linked Respiration, (B) Maximal Respiratory Capacity and (C) Reserve Capacity are shown.