Table 2.
Pyrrolidine ring expansion by reaction with different nucleophilesa.
| Entry | Nucleophile | Yield (%) | |
|---|---|---|---|
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||
| 36a−e | 36a−e | ||
| 1 | ![]() |
46 | 32 |
| 2 | ![]() |
56 | 37 |
| 3 | ![]() |
11 | 89 |
| 4 | ![]() |
23 | 56 |
| 5 | ![]() |
35 | 23 |
Reaction conditions: 33: 35a-e in 1: 1 molar ratio, in ACN heated in a autoclave to 180°C for 5–24 h.






